Investigator

Neeloffer Mookherjee

Ph.D.

  • Accepting Students: Yes
  • Research Category: Childhood Diseases

Contact

Current Positions

Professor, Departments of Internal Medicine and Immunology
CIHR Sex and Gender Science Chair - Respiratory & Circulatory Health
Chair WISDOM (Women in Science: Development, Outreach & Mentoring)
Biology of Breathing Research Group; Children's Hospital Research Institute of Manitoba

Education

2004 – 2008 Postdoctoral Research Associate, University of British Columbia, Vancouver, Canada
2001 – 2001 Postdoctoral Fellow, Vaccines & Infectious Diseases Org., Saskatoon, Canada
1995 – 2001 Ph.D. in Microbiology, University of Victoria, Canada
1990 – 1993 M.Sc. in Microbiology, University of Bombay, India
1986 – 1989 B.Sc. in Microbiology (Major), University of Bombay, India

Research Focus

Overall Vision: To advance the fundamental understanding of Molecular Processes in Chronic Inflammation, and harness the Biology of Cationic Host Defence Peptides to develop immunomodulatory therapy for chronic disease.

Specific Research Focus:

​To define molecular processes in the regulation of inflammation, including biological sex-related differences, in chronic inflammatory disease, with focus on asthma.

​To examine immunity related functions, including regulation of inflammation, by Cationic Host Defence Peptides (also known as antimicrobial peptides).

​​​To develop small synthetic derivatives of host defence peptides, known as Innate Defence Regulator (IDR) Peptides, as immunomodulatory therapy for asthma.

​​​To investigate impact of environmental pollutants of the lung and plasma proteome, in the context of chronic respiratory disease such as asthma.

Research Interests

- Immunology of lung inflammation
- Asthma
- Regulation of inflammation by host defense peptides
- Air Pollution
- Proteomics