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Saeid Ghavami PhD

Currently accepting students.

Current Position

Researcher, Children’s Hospital Research Institute of Manitoba; Assistant Professor, Department of Human Anatomy and Cell Science, College of Medicine, Faculty of Health Sciences, University of Manitoba; Honorary Professor, Health Policy Research Centre, Shiraz Medical University, Shiraz, Iran.

History

Since 2007, I have been involved in researches, which has been focused on the application of apoptosis/autophagy/unfolded protein response in developing new asthma therapy strategies as a postdoctoral fellow. As a new investigator I am extending my previous research in developing novel treatments targeting autophagy/unfolded protein response to modulate epithelial mesenchymal transition for possible targeting of airway remodeling.

Education

December 2012-October 2013: Postdoctoral Fellow, St. Boniface Research Centre, University of Manitoba, Winnipeg, Canada.

  • November 2012-December 2012: Visiting Scholar, Apoptosis Research Centre, National University of Ireland, Galway, Ireland.
  • July 2007-October 2012: Postdoctoral Fellow, Manitoba Institute of Child Health, Department of Physiology, University of Manitoba, Winnipeg, Canada.
  • November 2004-July 2007: Postdoctoral Fellow, Manitoba Institute of Cell Biology, Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Canada.
  • September 1998-March 2004: PhD Candidate (Clinical Biochemistry), Department of Clinical Biochemistry, School of Medicine, Tarbiat Modarres University, Tehran, Iran.
  • September 1993-March 1996: MSc Student (Clinical Biochemistry), Department of Clinical Biochemistry, School of Medicine, Tarbiat Modarres University, Tehran, Iran.
  • February 1984-July 1989: BSc Student (Pure Chemistry), Department of Chemistry, Faculty of Science, Shiraz University, Shiraz, Iran.

Research Focus

In past 10 years, my research has been focused on developing new therapeutic approaches in lung cancer, cardiopulmonary diseases, and infection disease based on modification of apoptosis, autophagy, and unfolded protein response (UPR) pathway. My long-term research plan will be built based on the following major topics:

  • Role of Autophagy and UPR in Regulation of Transforming Growth Factor beta 1 (TGF-b1)-induced Epithelial Mesenchymal Transition (EMT) in Lung Cancer Model
  • Targeting Mevalonate Cascade as New Approach for Breast Cancer Therapeutic Strategies
  • Modulation of Influenza Virus Replication by Targeting Apoptosis/Autophagy/UPR