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Demitre Serletis BSc, MD, PhD, FRCSC, FAANS, FACS

Currently accepting students.

Current Position

Neurosurgeon, Winnipeg Children’s Hospital/Health Sciences Centre

Assistant Professor, Departments of Surgery and Pediatrics, University of Manitoba

Scientist, Children’s Research Institute of Manitoba

History/Education

2001, BSc (Biological Sciences), University of Calgary, Canada

2003, MD (Medicine), University of Calgary, Alberta, Canada

2010, PhD (Physiology & Biomedical Engineering), University of Toronto, Ontario, Canada

2012, FRCSC (Neurosurgery), University of Toronto, Ontario, Canada

2012 – 2013, Epilepsy Surgery Fellowship, Cleveland Clinic, Ohio, USA

2013, Gamma Knife Radiosurgery Certification, Cleveland Clinic, Ohio, USA

Research Focus

Our lab focuses on the study of biosignals acquired in vivo during the standard work-up of epilepsy patients with medically refractory seizures, as they are assessed for potential surgical candidacy at our center. Specifically, we aim to apply neuroengineering techniques drawing on nonlinear dynamics, complexity theory and fractal methods, to investigate extra- and intra-cranial human EEG brain recordings. In this way, one is able to mathematically characterize subtle changes therein, that may be used to identify, classify, and potentially predict transitions from the healthy to the epileptic state, and which may be used for monitoring and/or therapeutic purposes.

We also hold diverse research interests in the study of neural networks servicing language, memory and other cognitive functions, that lend themselves to further study with intracranial electrodes. By combining improved imaging capabilities and intracranial EEG recordings, there is a wealth of knowledge to be gained in enhancing our understanding and characterization of 3D networks within the brain. This knowledge could be used to eventually modulate and/or restore brain function using surface (wearable) and/or implantable (brain-computer interface) technologies. This is a growing field of interest in the research community, with tremendous clinical potential for pediatric and adult patients afflicted with neurological and/or neurosurgical disease.

In addition, we seek to explore other computationally-based research interests in the neurosciences, including studying the value of virtual reality-based methods for educational and clinical purposes.