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Trainee of the Month, Upcoming Events, Trainee Accomplishments, Trainee Profiles, Student Resources
Welcome to BReaTH (The Biology of Breathing Research Trainee’s Hub). Biology of Breathing (BoB) offers a multidisciplinary and interactive training environment for basic and clinical science post-doctoral fellows, graduate students, and undergraduate summer students.
Name/Position: Mirna Ragheb, Summer Student
PI: Dr. Andrew Halayko
Where are you from? Egypt
What was your training before coming to your lab? I finished my third year of the Bachelor of Nursing program at U of M. I did not have any previous training in research before joining the lab last summer.
What is your research focused on? My project this summer focuses on the role of oxidized phosphatidylcholine (OxPC) in asthma. More specifically, I try to learn more about the signaling pathway of OxPC in human airway smooth muscle cells.
What are hobbies/interests away from the lab? Reading, cycling, cooking
What is your long term plan? I plan to work as a registered nurse in an internal medicine unit.
What is something on your bucket list? Visit Magdi Yacoub Foundation Aswan Heart Center
If you could have dinner with anyone who would it be? Sir Magdi Yacoub, one of the world’s most famous cardiothoracic surgeons
Name/Position: Daisy Liu
PI: Dr. Richard Keijzer
Where are you from? Winnipeg, MB
What was your training before coming to your lab? Bachelor of Science Degree at Queen’s University
What is your research focused on? Congenital diaphragmatic hernias and congenital pulmonary airway malformation particularly in newborns
What are hobbies/interests away from the lab? I enjoy dancing, music, and going on food adventures.
What is your long term plan? Complete my medical degree and residency
What is something on your bucket list? Living in Italy and Greece for a few months to years
If you could have dinner with anyone who would it be? Massimo Bottura owner of Osteria Francescana, a 3 Michelin star restaurant in Modena Italy eating his pasta
Name/Position: Landon Falk, Summer Student
PI: Richard Keijzer
Where are you from? Winnipeg Manitoba
What was your training before coming to your lab? I had only had very basic training in my labs in university, so I didn’t know what to expect! Over the past 3 years I have developed so many valuable and interesting skills that are applicable both in the lab and in everyday life.
What is your research focused on? Our lab is interested in the abnormal lung development in babies born with Congenital Diaphragmatic Hernia meaning they have a hole in their diaphragm and abnormally stiff lungs, it is our goal to fix this abnormal lung development before the babies are born. In our lab we study microRNA’s which are small non-coding RNA’s that regulate gene expression, more specifically we are looking at the role of miR-200b in hypoplastic lung development.
What are hobbies/interests away from the lab? In my spare time I like to relax and spend time with my dog. I also love working with children and teach swimming lessons as well as tutor children with autism.
What is your long term plan? Currently, my long term plan is to go to medical school and become a pediatric oncologist, I’m in the process of preparing for the MCAT this summer so we will see what happens!
What is something on your bucket list? I would really like to travel to Europe
If you could have dinner with anyone who would it be? I would really love to be able to sit down and have dinner with my entire family at once.
“Pragmatic Trial Design”
Northern Great Plains Lipid Conference (June 3-4, 2017):
Thomas Mahood: Changes in lung tissue proteome in an allergen challenge mouse model of asthma.
Aruni Jha: Peroxidation of phosphatidylcholine: a signature for allergen- induced airway responses and allergen specificity.
Aruni Jha: Cigarette smoke exposure generates a unique peroxidized phosphatidylcholine fingerprint in the lung.
Dr. Chris Pascoe: Oxidized phosphatidylcholine induces cox2 gene expression and cytokine secretion by human airway smooth muscle cells.
Dr. Chris Pascoe: Oxidized phosphotidylcholine, a bioactive product of oxidative damage, causes airway epithelial barrier impairment.
Dr. Chris Pascoe: Intranasal simvastatin prevents allergen challenge-induced changes in lipid metabolites (talk).
Thomas Mahood: Prenyltransferase expression and function in lung fibroblasts from moderate copd patients (talk).
Naghmeh Khoshgoo “MicroRNA-200b regulates distal airway development by maintaining epithelial integrity” Nature Scientific Reports (Accepted May 30th, 2017)
Project: “Role of oxidized phospholipids in the pathophysiology of asthma”
Supervisor: Dr. Andrew Halayko
Current Chair of BReaTH
Project: “The Role of Protein Prenylation in Asthma and COPD”
Executive Member of BReaTH
Project: “Mechanobiology regulation of airway epithelial barrier function”
Supervisor: Dr. Adrian West
Project: “Role of Microrna-200b in Normal and Abnormal Lung Development Associated with Congenital Diaphragmatic Hernia”
Supervisor: Dr. Richard Keijzer
Past Chair of BReaTH
Supervisor: Neeloffer Mookherjee
Project: “Effect of Simvastatin on Airway Inflammation and Hyperresponsiveness”
Past Head of BReaTH
Project: “Methylome of Infant Diabetes”
Supervisor: Dr. Vern Dolinsky
Project: “Enhanced Expression of GPCRs in Autoimmune Diagnotics”
Supervisor: Dr. Prashan Chelikani
For more information contact the BReaTH team email@example.com
Grants, Awards, Travel
Grants and Awards Guide 2017
Travel Grant Checklist
Travel Grant Application
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University of Manitoba Physiology Student Handbook
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CHRIM PowerPoint Template
Biology of Breathing (BOB)
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Canadian Thoracic Society Tool Kit
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